Searchable abstracts of presentations at key conferences in endocrinology

ea0086p203 | Metabolism, Obesity and Diabetes | SFEBES2022

Monitoring obesity-induced hyperglycaemia and insulin sensitivity in obese murine pregnancy

Morris Jessica , Kennard Matilda , Farrel-Dillon Keith , Taylor Paul , Bowe James , Gnudi Luigi , Nandi Manasi , Chapple Sarah

During pregnancy progressive maternal insulin resistance occurs which is normal, ‘sparing’ glucose that can be transported across the placenta to be used by the fetus. In gestational diabetes mellitus (GDM) maternal glucose dysregulation is exacerbated, characterised by hyperglycaemia and associated with long-term adverse outcomes in mother and child, such as increased risk of diabetes and/or cardiovascular disease in later-life. Continuous glucose monitoring (CGM) i...